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https://doi.org/10.21860/medflum2018_207365

Dyskinesia-hyperpyrexia syndrome – a new medical emergency in Parkinson’s disease: case report

Manca Nikić orcid id orcid.org/0000-0002-1625-3841 ; Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Vladimira Vuletić ; Medicinski fakultet Sveučilišta u Rijeci, Rijeka, Klinika za neurologiju, KBC Rijeka, Rijeka


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Abstract

Aim: Dyskinesia-hyperpyrexia syndrome is a rare case of medical emergency in Parkinson's disease caused by excessive dopaminergic stimulation. It is characterized with severe continuous dyskinesias associated with rhabdomyolysis, hyperthermia, and subsequent alteration of the mental state. The aim of this paper is to present a clinical case of a patient suffering from Parkinson's disease presenting with dyskinesia and hyperpyrexia. Case report: We present a case of a fifty-five-year-old patient who presented with fifteen-day high body temperature and worsening of dyskinesia. The patient, in spite of a detailed clinical examination and laboratory examination, was unidentified as such. In the further course of the treatment, the condition of the patient deteriorated in the sense of extreme hyperpyrexia with the development of respiratory insufficiency and circulatory instability. After four weeks of treatment in the Intensive Care Unit, a patient with severe autonomic dysfunction, passed away. Conclusion: This case points out the importance of early recognition of dyskinesia and hyperpyrexia as an emergency in Parkinson's disease with the aim of early medical support and the prevention of life-threatening consequences.

Keywords

dyskinesia; hyperpyrexia; Parkinson's disease

Hrčak ID:

207365

URI

https://hrcak.srce.hr/207365

Publication date:

1.12.2018.

Article data in other languages: croatian

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