Acta clinica Croatica, Vol. 57. No. 2., 2018.
Original scientific paper
https://doi.org/10.20471/acc.2018.57.02.10
Flow Changes in Orbital Vessels Detected with Color Doppler Ultrasound in Patients with Early Dysthyroid Optic Neuropathy
Mladen Lešin
; Department of Ophthalmology, Split University Hospital Center, Split, Croatia
Veljko Rogošić
; Department of Ophthalmology, Split University Hospital Center, Split, Croatia
Lucija Vanjaka Rogošić
; Dr. Vanjaka Rogošić Dermatovenereological Surgery, Split, Croatia;
Igor Barišić
; Department of Radiology, Split University Hospital Center, Croatia;
Goran Pelčić
; Department of Radiology, Split University Hospital Center, Croatia;
Abstract
Thyroid-associated orbitopathy (TAO) is a common manifestation of Graves’ disease. Th e aim of the study was to assess the six percent of patients with TAO that develop dysthyroid optic neuropathy (DON), which is the most serious complication of TAO. As DON can cause permanent damage, it is essential to detect DON early when visual loss is still reversible. Color Doppler ultrasound is a noninvasive diagnostic method, which may be useful in early detection of DON. Th irty-six patients with confi rmed Graves’ disease and active TAO were included, 21 (58%) of them with early DON (eDON) and 15 (42%) free from any signs of eDON. All study patients underwent Doppler ultrasound examination to determine the blood fl ow rates in the internal carotid artery, ophthalmic artery, and central retinal artery. Study results showed color Doppler ultrasound examination to have a potential to detect orbital blood fl ow changes in patients with eDON. Early detection of DON may result in earlier treatment and prevention of permanent optic nerve damage.
Keywords
Graves’ Ophthalmopathy; Graves’ Disease; Optic Nerve Diseases; Ultrasonography, Doppler Color; Optic Nerve Injuries
Hrčak ID:
207544
URI
Publication date:
1.6.2018.
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