Short communication, Note

A General Method · for the Synthesis of Y- and d - Keto Esters

S. Pavlov ; Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Yugoslavia
V. Arsenijević ; Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Yugoslavia

Abstract

A method for th'e preparation of y- and 1\-keto esters is
described. The sodio derivative of 1,1-di-tert-butyl-2-ethylethanetricarboxylate or 1,1-di-tert-butyl-3-ethylpropanetricarboxylate is acylated with a carboxylic acid chloride. Elimination of tert-butyl
groups and decarboxylation are accomplished by heating the
acylated triester in toluene with a catalytic amount of p -toluenesulphonic
acid. Under these conditions the carbethoxy group
remains unattacked.

Keywords

Hrčak ID:

207944

URI

https://hrcak.srce.hr/207944

Publication date:

1.2.1970.

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