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Short communication, Note

Synthesis of 1, 5-Dioxopentane-bis-( 4-hydroxyiminoformy 1- pyridinium) Dichloride

Z . Binenfeld ; High Military Technical School, Zagreb, Croatia, Yugoslavia
M. Orlov ; High Military Technical School, Zagreb, Croatia, Yugoslavia
D. Rakin ; High Military Technical School, Zagreb, Croatia, Yugoslavia
M. Milojević ; High Military Technical School, Zagreb, Croatia, Yugoslavia


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Abstract

Fifteen years ago Wilson demonstrated1 that hydroxylamine is capable
of reactivating to a certain degree acetylcholine esterase inhibited by organophosphorus compounds . The same kind of activity was found in a numb er of hydroxamic acids which were not suitable for therapeutic use and also in several pyridinium mono- and dioximes. Among the latter class of compounds the best results were obtained with different 2- or 4-hydroxyiminoformylpyridinium salts of structure I and II2 • 3 •

Keywords

Hrčak ID:

208088

URI

https://hrcak.srce.hr/208088

Publication date:

15.10.1967.

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