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Short communication, Note

A Note on the Synthesis of 1-Naphthyl-14 C-Isocyanate and Ethyl B-[3-(1' -naphthyl)-ureido-2-14CJ Butyrate

D. Keglević ; Tracer Laboratory, Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia
B. Leonhard ; Tracer Laboratory, Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia


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Abstract

The most converuiem way ,of oib.tailni.ing the 1tJitle ureidoester1 (II) semed to be the action of 1-naphthyl- 14 C -isocyanate (I) on ethyl ~-aminobutyrate. A searchof the literature revealed that the preparation of 1- or 2-naphthyl- 14C-isocyanate was not described. As 1-naphthoic- 14 C-acid was synthesized2 in a good yield by one step reaction from Ba 14C03 and 1-bromonaphthalene, we investigated the optimal conditions under which I could be obtained from this acid. In inactive runs 1-naphthoyl chloride was treated with sodium azide by the wet and the dry method3 respectively.

Keywords

Hrčak ID:

208437

URI

https://hrcak.srce.hr/208437

Publication date:

15.1.1962.

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