Medicus, Vol. 11 No. 1_Farmakologija, 2002.
Review article
ACE Inhibitors in the Treatment of Hypertension and Congestive Heart Failure in Family Physician Practice
Slavko Lovasić
Margita Rušinović
Abstract
The purpose of antihypertensive treatment is
to achieve normotension with blood pressure value below
140/85 mmHg. Besides unavoidable general measures
which are obligatory for all patients with hypertension, various
drugs are available in therapy of hypertension and congestive
heart failure. Prescribing of ACE inhibitor drugs in treatment of
hypertension during the last decade is among the highest in
general (family) practice. Adverse factors for individual drugs
can differ in their long term therapy and/or use in individual
patients, therefore ACE inhibitors together with diuretics and
beta blockers are the most studied drugs regarding risk reduction.
Their usefulness is evident in hypertensive patients with
initial heart failure, diabetes with microalbuminuria and
patients with renal lesion. Wide indication range and relatively
noticeable and easily controllable side effects give ACE
inhibitors high rank in everyday use but also point to danger
of uncontrolled usage.
Keywords
hypertension; kongestive heart failure; risk factors; therapy; ACE inhibitors
Hrčak ID:
19949
URI
Publication date:
13.2.2002.
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