Short communication, Note
https://doi.org/10.5513/JCEA01/19.4.2367
Rabbit myostatine gene polymorhism (c.747+34C>T and c.194A>G) as a marker for meat production
Alica Navratilova
; Department of Genetic and Animal Breeding Biology, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic
Miroslava Požgajova
; AgroBioTech Research Centre (ABT RC), Slovak University of Agriculture in Nitra, Nitra, Slovakia
Anna Trakovicka
; Department of Genetic and Animal Breeding Biology, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic
Jan Rafay
; NPPC Research Institute for Animal Production in Nitra, Slovak Republic
Abstract
Myostatin gene (MSTN or GDF-8) affects both, the amount and composition of muscle fibers. MSTN plays a key role in muscle growth and it has applications in breeding and animal husbandry. Polymorphic variants of this gene are associated with growth rates and carcass yield of different species. This study is focused on two single nucleotide polymorphisms: MSTN SNP c.747+34C>T and MSTN SNP c.194A>G and their effect on selected production traits. Genomic DNA was extracted from whole blood. Polymorphic variants of MSTN gene were detected using PCRRFLP method. Association studies revealed significant positive effect of allele T (c.747+34C>T) and allele G (c.194A>G) on meat performances in tested rabbit population.
Keywords
association studies; GDF-8; meat production; MSTN; rabbit
Hrčak ID:
213727
URI
Publication date:
18.12.2018.
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