Original scientific paper
https://doi.org/10.24141/1/5/1/1
Possibilities and difficulties in cytological diagnosis of neurinoma
Barbara Korov
orcid.org/0000-0003-1243-0350
; University of Applied Health Sciences, Zagreb, Croatia
Karmen Trutin Ostović
; Clinical Unit of Cytology in Clinical Department of Pathology and Cytology, Dubrava University Hospital, Zagreb; University of Applied Health Sciences, Zagreb, Croatia
Ivica Lukšić
; Clinic of Maxillofacial Surgery, Dubrava University Hospital, Zagreb; School of medicine, Zagreb, Croatia
Berislav Rožman
; Clinical Unit of Nuclear Medicine in Clinical Department of Diagnostic and Interventional Radiology, Dubrava University Hospital, Zagreb, Croatia
Igor Čikara
; Clinical Unit of Ultrasound in Clinical Department of Diagnostic and Interventional Radiology, Dubrava University Hospital, Zagreb, Croatia
Danko Müller
; Clinical Unit of Pathology in Clinical Department of Pathology and Cytology, Dubrava University Hospital, Zagreb, Croatia
Spomenka Manojlović
; Clinical Unit of Pathology in Clinical Department of Pathology and Cytology, Dubrava University Hospital, Zagreb, School of medicine, Zagreb, Croatia
Abstract
Neurinoma (schwannoma) is a rare benign tumor that originates from Schwann cells of the nerve sheath. Neurinoma is a slow-growing, solitary and encapsulated tumor. These neoplasms may occur at any age but are more common between the ages of 30 and 60. Neurinoma of the head and neck occurs in younger people, at the ages of 20 and 30. Cytological diagnosis is important for the accurate treatment, detection of recurrence of the disease and diagnosing a new neurinoma on another nerve. Fine needle aspiration cytology (FNAC) can be done with or without ultrasound guidance. During 7 years - from 1 January 2007 until 31 December 2013, 14 322 FNAC have been done at the Department of Cytology and Cytometry, Dubrava University Hospital and only 10 (0.07%) patients had cytological diagnosis of neurinoma. The most FNAC of neurinoma was done in the head and neck, in 7 patients out of 10. We have analysed retrospectively cytology slides and reports and we determined the accuracy of cytology by comparing cytological diagnoses with pathohistological findings. Cytological diagnosis of neurinoma was accurate in 6 patients according to pathohistological diagnosis. In 4 patients with pathohistological diagnosis of neurinoma cytological diagnoses were mesenchymal tumor in 3 patients and spindle cell tumor in one patient, all of them were benign lesions.
Keywords
neurinoma; cytology; fine-needle aspiration cytology (FNAC)
Hrčak ID:
217955
URI
Publication date:
18.3.2019.
Visits: 3.780 *