Review article

C-Reactive Protein and Serum Amyloid A as Biomarkers for Canine and Human Diseases

Nejra Hadžimusić ; Veterinarski fakultet Univerziteta u Sarajevu, Bosna i Hercegovina

Abstract

The acute phase response of inflammatory reaction is manifested by increased synthesis of specific proteins known as acute phase proteins. Acute phase proteins include the C-reactive protein, serum amyloid A, haptoglobin, alpha-1-glycoprotein, fibrinogen, α 1 acid glycoprotein, ceruloplasmin and others. These proteins are mostly synthesised by the hepatocytes. This review article outlines the concentration values of these acute phase proteins monitored in pathological conditions in dogs and humans. Recent studies indicated the significance of these proteins for diagnosis and monitoring the course and outcome of different diseases.

Keywords

Acute phase response; C-reactive protein; Serum amyloid A; Biomarkers

Hrčak ID:

221738

URI

https://hrcak.srce.hr/221738

Publication date:

21.2.2017.

Article data in other languages: croatian

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