Medicus, Vol. 12 No. 2_Spolne bolesti, 2003.
Review article
Urinary Tract Infections - Current Issues in Pathogenesis and Treatment
Višnja Škerk
Abstract
Urinary tract infections (UTI) are symptomatic,
asymptomatic, acute (first or single), recurrent, chronic,
complicated and uncomplicated. Clinical symptoms of cystitis
and leukocituria are reasons enough to start a 3-day
empiric antimicrobic therapy of acute uncomplicated cystitis
in young women. Urinoculture must be done before the onset
of antimicrobic therapy in pregnant women, diabetics, recurrent
UTI, pyelonephritis, and in cases of unsuccessful previous
treatment. Treated should be all symptomatic UTI, while
asymptomatic bacteriuria should be treated only in pregnant
women, diabetics, pre-school children with abnormal urinary
tract, newborns and before urological-gynecological surgery
as well as in receptors of transplanted kidney. In complicated
UTI it is important to establish and to try to eliminate, or
at least to control, factors which complicate the particular
case. For treatment of UTI are used fluorokinolons, beta-lactamic
antibiotics, aminoglykosides, cotrimoxazole, nitrofurantoin
etc. Cystitis can be treated 3 or 7 days, asymptomatic
bacteriuria 3 to 7 days, uncomplicated pyelonephritis
10 to 14 days. For chronic and complicated UTI 7 to 14 days
treatment is recommended only in relapses and reinfections,
and in chosen patients for several weeks, up to 6 months.
Chemoprophylaxis of recurrent uncomplicated UTI is performed
for at least 6 months.
Keywords
urinary tract infections; antimicrobic medications; treatment; microbiology
Hrčak ID:
20573
URI
Publication date:
7.10.2003.
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