Original scientific paper

Diagnosis and treatment of hyperadrenocorticism in dogs

Gabrijela Jurkić Krsteska ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Iva Šmit ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Marija Lipar ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Karol Šimonji ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Ljiljana Bedrica ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Ljerka Fučkala ; Ministarstvo poljoprivrede Repubike Hrvatske, Zagreb, Hrvatska
Tugomir Karadjole ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska

Abstract

In this research, six dogs aged 10 to 13 years old (4 males and 2 females) were exam- ined. In four dogs, polyuria and polydipsia were recorded. In one case, the owners noted only hair loss in the neck. One dog was not suffering from polyuria or polydipsia. The owners noted only visual disturbances (poor eyesight), overconsumption of food and being overweight. One dog underwent a medical examination due to the presence of blood in its urine. All the dogs were clinically exam- ined, blood was taken for hematological and biochemical tests, and radiography was per- formed as necessary. After hyperadrenocorti- cism was suspected, an ACTH stimulation test was performed. All the dogs were positive. All the dogs received initial therapy and blood work was performed on a regular basis. Ten days after the initial therapy, basal and stim- ulated cortisol levels were within normal levels in all the dogs. No significant variation was ob- served in the hemogram for all the dogs. In con- trast, in biochemistry tests alanine aminotrans- ferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALKP), triglyceride (TRIG) and cholesterol (CHOL) levels were significantly elevated prior to and after the initial therapy. The survival time was on average 2.5 to 10 months. Only one dog lived for one and a half years after hyperadrenocorticism had been diagnosed.

Keywords

hyperadrenocorticism; diagnosis; therapy; dog

Hrčak ID:

223050

URI

https://hrcak.srce.hr/223050

Publication date:

22.7.2018.

Article data in other languages: croatian

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