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Review article

Semen evaluation:can we forecast fertility?

Heriberto Rodriguez-Martinez orcid id orcid.org/0000-0002-5194-2124 ; Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden


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Abstract

This review critically comments on established and emerging methods of semen evaluation that would foresee the fertility of the ejaculate (neat or processed) or the male. Functional sperm testing through biomimetic in vitro assays are priority since these, by resembling events during sperm transport, storage and interaction with the female genital tract and the oocyte, best provide clues for sperm selection and the role of sperm sub-populations in the ejaculate. The review also focuses on the exploration of the genome, the transcriptome and the proteome of both spermatozoa and the seminal plasma which may help to unveil how spermatozoa and seminal plasma components would signal to the female and link to fertility and even prolificacy. Specific seminal plasma components, both among individuals and portions of the ejaculate, not only relate to sperm survival but also to signal the female immune system towards a differential immune tolerance warranting fertility.

Keywords

semen analysis; sperm quality; in vitro methods; fertility estimation

Hrčak ID:

223835

URI

https://hrcak.srce.hr/223835

Publication date:

28.7.2019.

Article data in other languages: croatian

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