Professional paper
https://doi.org/10.15644/asc53/3/9
Oralna mukormikoza i aspergiloza kod bolesnika s akutnom leukemijom
Vanja Vučićević Boras
; Department of Oral Medicine School of Dental Medicine University of Zagreb and Department of Oral Diseases University Hospital Centre Zagreb, Zagreb, Croatia
Martin Jurlina
; Department of Otolaryngology, Head and Neck Surgery University Hospital Centre Zagreb, Zagreb, Croatia
Vlaho Brailo
; Department of Oral Medicine School of Dental Medicine University of Zagreb and Department of Oral Diseases University Hospital Centre Zagreb, Zagreb, Croatia
Katarina Đurić Vuković
; Department of Otolaryngology, Head and Neck Surgery University Hospital Centre Zagreb, Zagreb, Croatia
Pavle Rončević
; Department of Haematology University Hospital Centre Zagreb, Zagreb, Croatia
Sandra Bašić Kinda
; Department of Haematology University Hospital Centre Zagreb, Zagreb, Croatia
Danica Vidović Juras
; Department of Oral Medicine School of Dental Medicine University of Zagreb and Department of Oral Diseases University Hospital Centre Zagreb, Zagreb, Croatia
Dragana Gabrić
; Department of Oral Surgery School of Dental Medicine University of Zagreb and Department of Oral Surgery University Hospital Centre Zagreb, Zagreb, Croatia
Abstract
Bolesnik u dobi od 54 godine s akutnom limfoblastičnom leukemijom upućen je u Zavod za oralnu medicinu. Imao je primarnu refraktornu bolest i liječen je prema protokolima HOVON 71 i HAM. Šesnaest dana nakon početka primjene protokola HAM, bolesniku se pojavila oralna tamnocrvena/smećkasta lezija nepca i maksilarna vestibularna egzofitična lezija. Iz obiju su uzeti uzorci za biopsiju te su mikrobiološkom obradom potvrđeni Aspergillus fumigatus i Rhizopus genus. Liječenje bolesnika sastojalo se od inferiorne maksilektomije te intravenski posakonazola i amfotericina tijekom sljedećih 28 dana. Budući da se koinfekcija tim dvjema gljivicama iznimno rijetko pojavi u usnoj šupljini, česte su dijagnostičke i terapijske dileme.
Keywords
oralne bolesti; mukormikoza; aspergiloza; imunokompromitiran domaćin; leukemija
Hrčak ID:
225689
URI
Publication date:
26.9.2019.
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