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Acta stomatologica Croatica : International journal of oral sciences and dental medicine, Vol. 53 No. 3, 2019.

Professional paper

https://doi.org/10.15644/asc53/3/9

Oralna mukormikoza i aspergiloza kod bolesnika s akutnom leukemijom

Vanja Vučićević Boras ; Department of Oral Medicine School of Dental Medicine University of Zagreb and Department of Oral Diseases University Hospital Centre Zagreb, Zagreb, Croatia
Martin Jurlina ; Department of Otolaryngology, Head and Neck Surgery University Hospital Centre Zagreb, Zagreb, Croatia
Vlaho Brailo ; Department of Oral Medicine School of Dental Medicine University of Zagreb and Department of Oral Diseases University Hospital Centre Zagreb, Zagreb, Croatia
Katarina Đurić Vuković ; Department of Otolaryngology, Head and Neck Surgery University Hospital Centre Zagreb, Zagreb, Croatia
Pavle Rončević ; Department of Haematology University Hospital Centre Zagreb, Zagreb, Croatia
Sandra Bašić Kinda ; Department of Haematology University Hospital Centre Zagreb, Zagreb, Croatia
Danica Vidović Juras ; Department of Oral Medicine School of Dental Medicine University of Zagreb and Department of Oral Diseases University Hospital Centre Zagreb, Zagreb, Croatia
Dragana Gabrić ; Department of Oral Surgery School of Dental Medicine University of Zagreb and Department of Oral Surgery University Hospital Centre Zagreb, Zagreb, Croatia

Full text: croatian pdf 228 Kb

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Full text: english pdf 228 Kb

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Abstract

Bolesnik u dobi od 54 godine s akutnom limfoblastičnom leukemijom upućen je u Zavod za oralnu medicinu. Imao je primarnu refraktornu bolest i liječen je prema protokolima HOVON 71 i HAM. Šesnaest dana nakon početka primjene protokola HAM, bolesniku se pojavila oralna tamnocrvena/smećkasta lezija nepca i maksilarna vestibularna egzofitična lezija. Iz obiju su uzeti uzorci za biopsiju te su mikrobiološkom obradom potvrđeni Aspergillus fumigatus i Rhizopus genus. Liječenje bolesnika sastojalo se od inferiorne maksilektomije te intravenski posakonazola i amfotericina tijekom sljedećih 28 dana. Budući da se koinfekcija tim dvjema gljivicama iznimno rijetko pojavi u usnoj šupljini, česte su dijagnostičke i terapijske dileme.

Keywords

oralne bolesti; mukormikoza; aspergiloza; imunokompromitiran domaćin; leukemija

Hrčak ID:

225689

URI

https://hrcak.srce.hr/225689

Publication date:

26.9.2019.

Article data in other languages: english

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