Meeting abstract

https://doi.org/10.15836/ccar2019.236

Excessive daytime sleepiness as cardiovascular risk in Croatian obese patients

Filip Mustač orcid.org/0000-0003-2851-6183 ; University of Zagreb School of Medicine, Zagreb, Croatia
Martina Matovinović ; University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia
Tomislav Mutak ; University of Zagreb School of Medicine, Zagreb, Croatia
Barbara Barun ; University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia
Juraj Jug ; University of Zagreb School of Medicine, Zagreb, Croatia
Rea Levicki ; Požega General County Hospital, Požega, Croatia
Martina Lovrić Benčić ; University of Zagreb School of Medicine, Zagreb, Croatia; University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia
Ana Jelaković ; University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia
Bojan Jelaković ; University of Zagreb School of Medicine, Zagreb, Croatia; University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia

Abstract

Introduction: Excessive daytime sleepiness (EDS) is a very common complaint, especially in obese patients
and is a potentially alarming symptom related to many risk factors and comorbidities1. In obese patients
obstructive sleep apnea (OSA) is quite common. Our goal was to assess the connection between EDS and
hypertension in Croatian obese patients.
Patients and Methods: This cross-sectional study was carried out in a tertiary healthcare centre in an outpatient
clinic for treatment of obesity. 49 participants were included. Inclusion criterion was BMI>30 kg/m2.
Epworth Sleepiness Scale (ESS), consisting of 8 questions, every question ranged from 0-3 (overall range
0-24) was used to assess EDS. Spearman correlation coefficient, Welch t-test, chi-squared test and regression
analysis were used. They were divided into 4 and 3 categories. 4 categories: 0-7, 8-9, 10-15 and 16-24. Many
researches take ESS score 10 or greater as excessive daytime sleepiness, so our results were also interpreted
as 3 categories: 0-7, 8-9 and 10 or greater.
Results: Mean age of our participants was 50.29 ± 11.91 years. Overall mean BMI was 44.64±8.12 kg/m2. Results
on ESS divided into 4 categories (Figure 1) were statistically significant correlated to hypertension: χ2= 9.61;
p = .02. Also, results on ESS in 3 categories (Figure 2) were statistically significant correlated to hypertension:
χ2(2) = 9.43; p = .009. Results on ESS were not significantly connected to AHI index (ESS in 4 categories: χ2(9)=8.43, p=.49; ESS in 3 categories : χ2(6)=6.45, p=.37). Furthermore, results on ESS were not correlated to sex
(ESS in 4 categories χ2(3)=0.85, p=.84 and ESS in 3 categories: χ2(2)=0.56, p=.76).
Conclusion: Our results show that the presence of hypertension alters the result on the ESS and is most visible
in the so-called “borderline” area for the ESS score 8-9 in both divisions (into 3 and 4 categories), which
shows a possible underestimation of the risk of the population achieving the result on the ESS <10, which is
consistent with the studies of Borsini et al.2

Keywords

excessive daytime sleepiness; cardiovascular risk; obesity; hypertension.

Hrčak ID:

226705

URI

https://hrcak.srce.hr/226705

Publication date:

15.10.2019.

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