Professional paper
Antimicrobial Treatment of Oropharyngeal Mucositis During Radio(Chemo)Therapy Treatment of Patients with Head and Neck Cancer
Gordana Berić Jozić
orcid.org/0000-0002-4845-8390
; Oncology Clinic, University Hospital Mostar, Bosnia and Herzegovina
Ivana Tica Sedlar
; Oncology Clinic, University Hospital Mostar, Bosnia and Herzegovina
Krešimir Tomić
; Oncology Clinic, University Hospital Mostar, Bosnia and Herzegovina
Abstract
Oropharyngeal mucositis is a common side effect ocurring after a radio(chemo)therapy treatment of patients with head and neck cancer. It is manifested by erythema, ulceration, severe pain, and up to 85% of patients requiring liquid diet or disabled food/fluid intake. Mucositis is a limiting factor during treatment and symptomatic - supportive measures are necessary for maintaining life quality. Exacerbation can be caused by local infection or trauma. The role of antimicrobial therapy in prevention and treatment is debated and the results of clinical trials are mostly negative or mixed. This paper presents the frequency of oropharyngeal mucositis and the use of antimicrobial therapy in its prevention and treatment in 99 patients treated at Clinic of Oncology, University Clinical Hospital (UCH) Mostar. The incidence of mucositis has
been shown to be consistent with the data disclosed, and the use of antimicrobial drugs is mostly limited to the local application of antimycotics in therapeutic purposes.
Keywords
head and neck cancer; radiotherapy; oropharyngeal mucositis; antimicrobial treatment
Hrčak ID:
226999
URI
Publication date:
22.10.2019.
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