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Tuberculous Meningitis with Tuberculous Granulomas in Pregnancy – a Case Report
Olja Čuković
orcid.org/0000-0001-9700-8786
; Infectious Diseases Clinic, University Clinical Centre of the Republic Srpska, Banja Luka, Bosnia and Herzegovina
Antonija Verhaz
orcid.org/0000-0002-5558-976X
; Infectious Diseases Clinic, University Clinical Centre of the Republic Srpska, Banja Luka, Bosnia and Herzegovina
Tatjana Roganović
orcid.org/0000-0001-5469-5301
; Infectious Diseases Clinic, University Clinical Centre of the Republic Srpska, Banja Luka, Bosnia and Herzegovina
Irena Katan
; Infectious Diseases Clinic, University Clinical Centre of the Republic Srpska, Banja Luka, Bosnia and Herzegovina
Zorislava Bajić
; School of Medicine, University of Banja Luka, Bosnia and Herzegovina
Abstract
Tuberculous meningitis (TBM) is a severe consequence of Mycobacterium tuberculosis infection. Early clinical manifestations are often non-specific. In this case study, we showed tuberculous meningitis with tuberculous granulomas in a female patient during and after pregnancy, with all diagnostic and therapeutic dilemmas we had during her treatment. The patient was treated for 18 months. Our diagnostic findings showed extended pleocytosis and high protein level in cerebrospinal fluid (CSF), development of tuberculous granulomas in brain with relatively low inflammation parameters. Since it has been only a several days from the onset of the first symptoms to the beginning of treatment, the first signs of recovery showed very soon, despite development of the tuberculous granulomas. In the first 12 months tuberculostatic (TS) treatment was continuous, but after that period, treatment was intermittent for the next 6 months. After the treatment, a patient’s clinical and neurological status was normal as well as CSF analysis and neuroradiological findings.
Keywords
tuberculosis; tuberculous meningitis, tuberculous granuloma
Hrčak ID:
227001
URI
Publication date:
22.10.2019.
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