Liječnički vjesnik, Vol. 141 No. 9-10, 2019.
Review article
https://doi.org/10.26800/LV-141-9-10-38
Efficacy of uterobrush in endometrial sample collection for the cytology and diagnosis of endometrial lesions
Ines Krivak Bolanča
; Zavod za kliničku citologiju i citogenetiku, Klinička bolnica Merkur, Zagreb
Suzana Katalenić Simon
; Zavod za kliničku citologiju i citogenetiku, Klinička bolnica Merkur, Zagreb
Tanja Bota
; Odjel za patologiju i kliničku citologiju Opće bolnice Virovitica, Virovitica
Danijela Vincetić
; Odjel za patologiju i citologiju Opće bolnice Bjelovar, Bjelovar
Abstract
Objective: Endometrial carcinoma is the most common invasive neoplasm of the female genital tract, with a rising incidence over the past few decades. The aim of the study was to evaluate the efficacy of endometrial cytology using uterobrush in the collection of samples and diagnosis of endometrial lesions. Methods and examinees:
During the 12-month period direct endometrial samples by uterobrush were collected from 162 perimenopausal or postmenopausal symptomatic patients at Gynaecology Department at Merkur University Hospital. Results were compared with histology of the endometrium obtained by dilatation and curettage (n= 36), or hysterectomy (n=16), or the patients follow –up mainly by ultrasonography (n=97). Inadequate samples were excluded from the study. Results: Cytological findings were confirmed by histology in 69.2% (36/52) of cases.
Seven cancers, 13 hyperplasias, one polyp and 14 benign disorders were diagnosed and confirmed by histology. After using uterobrush device, patients who were followed-up by ultrasonography showed no gynaecological symptoms. Conclusion: Endometrial cytology by using uterobrush method can provide direct, adequate and
representative endometrial sample. Cytology can recognise endometrial lesions and provide data for an algorithm for further evaluation of symptomatic patients.
Keywords
ENDOMETRIUM – pathology; ENDOMETRIAL NEOPLASMS – diagnosis, pathology; ENDOMETRIAL HYPERPLASIA – diagnosis, pathology; CYTODIAGNOSIS – instrumentation, methods; SPECIMEN HANDLING – instrumentation
Hrčak ID:
229523
URI
Publication date:
12.12.2019.
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