Review article

https://doi.org/10.2478/acph-2021-0007

The use of Hericium erinaceus and Trametes versicolor extracts in supportive treatment in oncology

MATEUSZ WINDER orcid.org/0000-0003-3175-5660 ; Department of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice 40-027, Poland
WERONIKA BULSKA-BĘDKOWSKA ; Department of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice 40-027, Poland
JERZY CHUDEK ; Department of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice 40-027, Poland

Abstract

Substances available in nature with potential therapeutic effects are the subject of research that raises tremendous hopes for new challenges in medicine. Fungi are the most common organisms in the ecosystem and the most interesting in this respect. This review discusses two species of edible fungi, used for centuries in Eastern natural medicine, with the best-documented effect – Hericium erinaceus (He) and Trametes versicolor (Tv). The results of in vivo and in vitro studies conducted on mice and human cell lines demonstrate immunomodulatory, potentially, anticancer, antiinflammatory and neuroregenerative effects of substances isolated from these fungi. The substances contained in the extracts of He and Tv seem to have immunomodulatory effects that may support chemotherapy. The use of these extracts is justified stronger than the other supportive treatments based on supplements.

Keywords

Hericium erinaceus; Trametes versicolor; fungi; oncology; immunomodulation

Hrčak ID:

236192

URI

https://hrcak.srce.hr/236192

Publication date:

31.3.2021.

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