Short communication, Note

https://doi.org/10.2478/aiht-2020-71-3413

Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning

Tadej Petreski ; University Medical Centre Maribor, Clinic for Internal Medicine, Department of Nephrology, Maribor, Slovenia 2 University of Maribor Faculty of Medicine, Maribor, Slovenia
Barbara Kit ; University Medical Centre Maribor, Clinic for Internal Medicine, Intensive Care Unit, Maribor, Slovenia
Matej Strnad ; University of Maribor Faculty of Medicine, Maribor, Slovenia, Centre for Emergency Medicine, Prehospital Unit, Maribor, Slovenia
Damjan Grenc ; University Medical Centre Ljubljana, Clinic for Internal Medicine, Centre for Clinical Toxicology and Pharmacology, Ljubljana, Slovenia

Abstract

Cholinergic syndrome is a common topic at western medical universities yet rarely observed in clinical practice. The treatment involves muscarinic antagonists, acetylcholinesterase reactivation, seizure control, and supportive measures. Here we report a case of a 52-year old Caucasian male who attempted suicide by ingesting a purple crystal powder that turned out to be a mixture of carbofuran and chlormephos. At clinical examination, the patient presented with salivation, perspiration, diarrhoea, bradypnoea, loss of consciousness, and epileptic seizures. Laboratory tests showed low plasma cholinesterase, and we started obidoxime along with supportive intensive care treatment. He was later transferred to the psychiatry department for further diagnostics and treatment.

Keywords

carbofuran; chlormephos; critical care; obidoxime

Hrčak ID:

239266

URI

https://hrcak.srce.hr/239266

Publication date:

17.6.2020.

Article data in other languages: slovenian

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