Acta clinica Croatica, Vol. 59. No. 2., 2020.
Other
https://doi.org/10.20471/acc.2020.59.02.22
Primary Hodgkin’s Lymphoma of the Breast Initially Treated by Surgical Excision and Axillary Dissection
Ingrid Marton
; Department of Obstetrics and Gynecology, Sveti Duh University Hospital; Croatian Catholic University, Zagreb, Croatia;
Zlatko Hrgović
; Praxis Prof. Zlatko Hrgovic, Frankfurt am Main, Frauenklinik Offenbach, Offenbach, Germany
Dubravko Habek
; Department of Obstetrics and Gynecology, Sveti Duh University Hospital; Croatian Catholic University, Zagreb, Croatia;
Abstract
Primary breast lymphoma accounts for 0.04%-0.5% of all breast malignancies. Primary non-Hodgkin’s lymphomas of the breast are extremely rare and represent approximately 0.38%-0.7% of all cases. Epstein-Barr virus (EBV) has been postulated to play an important role in the pathogenesis of Hodgkin’s lymphoma. We present a case of EBV-positive primary Hodgkin’s lymphoma of the breast. Although there is no sufficient data on this challenging diagnosis, it is known that it could be misdiagnosed with inflammatory breast carcinoma. A crucial part of the proper histopathologic diagnosis is immunohistochemistry. Different modalities of treatment include operative procedure, chemotherapy and radiotherapy. Recent studies suggest chemotherapy and radiotherapy to
be initial treatment for patients with primary breast lymphomas.
Keywords
Primary breast lymphoma; Hodgkin’s lymphoma; Epstein-Barr virus; Immunohistochemistry
Hrčak ID:
243713
URI
Publication date:
1.6.2020.
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