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IMPORTANCE OF MACULAR OPTICAL COHERENCE TOMOGRAPHY IN EUROOPHTHALMOLOGY

TAMARA MIŠLJENOVIĆ VUČERIĆ orcid.org/0000-0002-4507-7533 ; Rijeka University Hospital Centre, Department of Ophthalmology, Rijeka, Croatia
TOMISLAV VIDOVIĆ orcid.org/0000-0003-1083-9195 ; Zagreb University Hospital Centre, Department of Ophthalmology, Zagreb, Croatia
TEA ČALJKUŠIĆ-MANCE ; Rijeka University Hospital Centre, Department of Ophthalmology, Rijeka, Croatia
BRANIMIR CEROVSKI ; retired ophthalmologist, Zagreb, Croatia

Abstract

Aim: The retinal nerve fi ber layer (RNFL) is made up of retinal ganglion cell axons. We evaluated sensitivity of optical coherence tomography (OCT) when measuring only RNFL or when a ganglion cell layer (GCL) analysis is added to the evaluation of optic neuropathy. Methods: This was a retrospective analysis of OCT in 348 patients examined at the neuro-ophthalmology department for suspicion of optic neuropathy during one year. OCT scans were taken with SOCT Copernicus REVO (Optopol Technology Sp. z.o.o.; software version 7.0.0). Results: Sensitivity of measuring RNFL alone was 37.6% (62/165) (with 95% confi dence interval (CI) 30.2%-45.5%) with 58.6% accuracy (165/292) (CI 95%: 52.7%-64.3%). When taking GCL in analysis, 103 patients (35.2%; 103/292) would be classifi ed as normal, false-negative if just RNFL measurements would be the only criterion for diagnosing optic neuropathy. Conclusions: OCT has become one of the most important tools in neuroophthalmic practice. It allows us to visualize axonal/neuronal integrity in the afferent visual pathway. Use of macular OCT with GCL analysis has contributed to the extended applicability of OCT in neuro-ophthalmology.

Keywords

optical coherence tomography; optic nerve disease; retinal ganglion cells

Hrčak ID:

244543

URI

https://hrcak.srce.hr/244543

Publication date:

6.10.2020.

Article data in other languages: croatian

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