Original scientific paper

Orientation in Friedel-Crafts Acetylation of Nerolineand Its 6-Alkyl Homologues

N. P. Buu-Hoi ; The Radium Institute, University of Paris, 26, rue d'Ulm, Paris, Ve
D. Lavit ; The Radium Institute, University of Paris, 26, rue d'Ulm, Paris, Ve
J. Collard ; The Radium Institute, University of Paris, 26, rue d'Ulm, Paris, Ve

Abstract

The Friedel-Crafts acetylation of neroline in nitrobenzene medium is shown to result predominantly either in 1- or in 6-substitution,depending on the experimental conditions; as a byproduct, 1,6-diacetyl-2-methoxynaphthalene is obtained. Further,it is shown that 6-alkylated nerolines such as 6-propyl-2-methoxynaphthalene, are acetylated in position 1, even in nitrobenzene medium, and that 1,6-dialkylated nerolines such as 6-ethyl-2-
methoxy-1-methylnaphthalene, can also be acetylated, whilst 1,6-dialkyl-2-naphthols are unable to undergo Nencki acylation reactions. In the course of this work, certain errors in the literature have been corrected.

Keywords

Hrčak ID:

246309

URI

https://hrcak.srce.hr/246309

Publication date:

30.12.1957.

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