Croatica Chemica Acta, Vol. 28 No. 3, 1956.
Original scientific paper
Syntheses in the 4-Substituted Thiosemicarbazide Series
M. Tišler
; Institute of Organic Chemistry, Technical Faculty, University of Ljubljana, Slovenia, Yugoslavia
Abstract
In connection with the investigations of tuberculostatic activity of arylthiosemicarbazides and arylthiosemicarbazones new 4-substituted thiosemicarbazides (I-XVIII) were synthesized. Condensation of these with aldehydes or ketones afforded the corresponding 4-substituted thiosemicarbazones (XIX-LVI). The attempted 'acetylation of p-nitrobenzaldehyde-4-phenylthiosemicarbazone and o - chlorobenzaldehyde - 4 - phenylthiosemicarbazone gave besddes acetanilide N,N.-diacetyl-p-nitrobenzylidenhydrazine (LVII) ,and N,N-dia cetyl-chlorobenzylidenehydrazine (LIX) .The 4-substituted thiosemic arbazides and thiosemiearbazones were tested for their tuberculostatic activity.
Keywords
Hrčak ID:
246841
URI
Publication date:
7.11.1956.
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