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Short communication, Note

A Synthesis of DL-a-Amino-B-hydroxy-valeric Acid. (Hydroxynorvaline)

D. E. Sunko ; Department of Physiology and Department of Chemistry, Medical Faculty, University of Zagreb, Croatia, Yugoslavia
A. Kisić ; Department of Physiology and Department of Chemistry, Medical Faculty, University of Zagreb, Croatia, Yugoslavia


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Abstract

By applying the method used by Pfister et al. for the synthesis of threonine we prepared DL-a-amino-B-hydroxy-valeric acid (hydroxynorvaline) starting from ethyl B-keto-valerate. This amino acid was prepared earlier by different methods by Osterberg , Abderhalden and Heyns , Botviillii.k et al, Euston et al., and by Izumiya. The melting points of hydorxynorvaline and of its N-benzoyl derivate indicate that the product obtained consists mainly of the threo-isomer.

Keywords

Hrčak ID:

249399

URI

https://hrcak.srce.hr/249399

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