Original scientific paper
https://doi.org/10.37797/ig.40.3.1
Antibacterial effect of „Sanosil super25“ on multiple resistant bacteria Acinetobacter baumannii and Klebsiella pneumoniae
Ana Kovačić
orcid.org/0000-0001-7857-1549
; Teaching Institute for Public Health of Split-Dalmatia County, Split
Jasna Hrenović
orcid.org/0000-0001-8513-3993
; University of Zagreb, Faculty of Science, Department of Biology, Zagreb
Ivana Goić-Barišić
orcid.org/0000-0002-1030-6092
; University of Split, Faculty of Medicine and Clinical Hospital Center Split, Split
Miroslav Barišić
; Health Center of Split-Dalmatia County, Dental practice Stari Grad, Island of Hvar
Abstract
Multi-resistant bacteria, the causes of nosocomial infections, such as Acinetobacter baumannii and Klebsiella pneumoniae, represent a global problem of the 21st century. The increasing resistance of these microorganisms to commercially available disinfectants is of a particular concern. The aim of our study was to determine disinfection effectiveness of the product "Sanosil super25", in relation to hydrogen peroxide, to multiple resistant isolates of A. baumannii and K. pneumoniae. The tested parameters were: MTC values (maximum tolerated concentration); MIC (minimum inhibitory concentration) and MBC (minimum bactericidal concentration). The MTC of Sanosil (<1.25 ppm) was twice as low as that of hydrogen peroxide. Sanosil MICs (1.25 or <1.25 ppm) were 4-fold lower than hydrogen peroxide. The MBC resulting in the absence of viable bacteria for Sanosil was <1.25 ppm after only 5 minutes of contact, which is at least 8 times lower concentration than hydrogen peroxide. The results showed that Sanosil super25 was more effective in all three categories, compared to hydrogen peroxide.
Keywords
Acinetobacter baumannii; Klebsiella pneumoniae; disinfection; Sanosil super25
Hrčak ID:
252502
URI
Publication date:
22.2.2021.
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