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Journal of Central European Agriculture, Vol. 22 No. 1, 2021.

Original scientific paper

https://doi.org/10.5513/JCEA01/22.1.2860

Industrial hemp (Cannabis sativa L.) as a possible source of cannabidiol

Jana PEXOVÁ KALINOVÁ orcid id orcid.org/0000-0002-1108-2246 ; Faculty of Agriculture, University of South Bohemia, Studentská 1668, České Budějovice 370 05, Czech Republic
Naděžda VRCHOTOVÁ ; Laboratory of Metabolomics and Isotopic Analyses, Global Change Research Institute, Academy of Sciences of the Czech Republic, Lipová 9, České Budějovice 370 05, Czech Republic
Jan TŘÍSKA orcid id orcid.org/0000-0003-3846-2158 ; Laboratory of Metabolomics and Isotopic Analyses, Global Change Research Institute, Academy of Sciences of the Czech Republic, Lipová 9, České Budějovice 370 05, Czech Republic
Šárka HELLEROVÁ ; Faculty of Agriculture, University of South Bohemia, Studentská 1668, České Budějovice 370 05, Czech Republic

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Abstract

(-)-Cannabidiol (CBD) is a cannabinoid, which has unique pharmacological and biological activities.The aim of this study was to determine the CBD, cannabidiolic (CBDA), and canabigerolic acids (CBGA) content in parts of industrial hemp that are possible waste material in the production of hemp fiber, and could be used for CBD extraction. Two hemp varieties were sampled at the full-flowering stage, and at the ripening stage. The lyophilised material (leaves, roots, stems, and inflorescences/seeds) was extracted with ethylacetate and analyzed by HPLC. Hemp inflorescences and leaves are the most important source of CBD. CBDA and CBGA are the dominant compounds in these plant parts. They are the precursors of CBD. The CBD level is dependent on the variety and the environmental conditions. Dry cool weather with lower solar intensity increased the CBD level in 'Bialobrzeskie' - a monoecious variety potentially suitable as a material for CBD extraction with heat decarboxylation due to the high CBDA, CBGA, and CBD levels in the leaves and inflorescences.

Keywords

cannabinoid; variety; inflorescence; cannabidiolic acid; canabigerolic acid; leaf; HPLC

Hrčak ID:

254966

URI

https://hrcak.srce.hr/254966

Publication date:

28.3.2021.

Article data in other languages: czech

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