Meeting abstract

Unilateral facial palsy and hearing loss as initial manifestation of Granulomatosis with polyangiitis: a case report

Franko Batinović ; Department of Otorhinolaringology with Head and Neck Surgery, University Hospital Center Split, Spinčićeva 1, 21 000 Split, Croatia
Marina Krnić Martinić ; Department of Otorhinolaringology with Head and Neck Surgery, University Hospital Center Split, Spinčićeva 1, 21 000 Split, Croatia
Davor Sunara ; Department of Otorhinolaringology with Head and Neck Surgery, University Hospital Center Split, Spinčićeva 1, 21 000 Split, Croatia

Abstract

Granulomatosis with polyangiitis (GPA) is a systematic autoimmune disorder characterized by necrotizing vasculitis of small to medium-sized-vessels and granuloma formation. GPA is commonly initially presented with respiratory and renal symptoms. Although involvement of the temporal bone is not unusual, an otologic disorder is rarely the presenting symptom. We present a case of a 36-year-old patient complaining of severe ear pain, hearing loss and unilateral facial palsy. After comprehensive clinical diagnostics and temporal bone and chest imaging, a multiorgan involving form of GPA was diagnosed. The patient was treated with cyclophosphamide and methylprednisolone which resulted in amelioration of ear pain, improvement of hearing loss, partial resolution of facial palsy and altogether clinical improvement of the patient. Although infrequently, systemic GPA can initially present with otologic symptoms and should not be overlooked as a possible cause of an otologic disorder resilient to usual pragmatic treatment.

Keywords

granulomatosis with polyangiitis; facial palsy; hearing loss; ear pain; case report

Hrčak ID:

256717

URI

https://hrcak.srce.hr/256717

Publication date:

8.4.2021.

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