Case report

Fever of unknown origin – Adult onset Still´s disease

Ivica Čabraja ; Opća bolnica "Dr. Josip Benčević", Slavonski Brod
Nenad Pandak ; Opća bolnica "Dr. Josip Benčević", Slavonski Brod
Marino Hanih ; Opća bolnica "Dr. Josip Benčević", Slavonski Brod
Josipa Fornet-Šapčevski ; Opća bolnica "Dr. Josip Benčević", Slavonski Brod
Branka Križanović ; Opća bolnica "Dr. Josip Benčević", Slavonski Brod
Marijan Šiško ; Opća bolnica "Dr. Josip Benčević", Slavonski Brod

Abstract

Fever of unknown origin (FUO) is a syndrome which includes fever higher than 38.3 °C (on several occasions) persisting without diagnosis for at least 3 weeks inspite of at least 1 week of hospital investigation. Among connective tissue diseases, adult onset Still´s disease (AOSD) is one of the most frequent cause of FUO. AOSD is a rare systemic inflamatory disorder of unknown etiology characterised by intermittent fever, arthralgia or arthritis, evanescent rash, sore throat, lymphadenopathy, hepatosplenomegaly, leukocytosis, elevated levels of hepatic enzymes and hyperferritinemia. Diagnosis of AOSD is made according to the diagnostic criteria, and by previously excluding infectious, malignant or reumatic diseases as possible causes of FUO. The authors report a patient with fever, arthralgia, sore throat, rash, lymphadenopathy, leukocytosis, hyperferritinemia and elevated levels of hepatic enzymes for whom the diagnosis of AOSD was made and whose condition and laboratory findings improved soon after the initiation of corticosteroid treatment.

Keywords

Fever of unknown origin; Adult onset Still´s disease; Ferritin

Hrčak ID:

23818

URI

https://hrcak.srce.hr/23818

Publication date:

11.12.2007.

Article data in other languages: croatian

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