Review article

https://doi.org/10.21860/medflum2021_261186

Advances in the diagnosis of malignant pleural mesothelioma

Martina Murković orcid.org/0000-0003-3177-3850 ; Klinički zavod za patologiju i citologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska
Ana Benvin ; Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska
Christophe Štemberger ; Klinički zavod za patologiju i citologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska
Danijela Vrdoljak-Mozetič ; Klinički zavod za patologiju i citologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska

Abstract

Malignant pleural mesothelioma (MPM) is an agressive neoplasm with an increasing incidence rate. MPM has a delayed onset of symptoms, and diagnosis is often challenging because of the difficulties in the differentiation of the benign and malignant lesions. CT (Computed tomography) is used for imaging assessment of mesothelioma, while biopsy and histopathology give the definitive confirmation of the MPM. Cytology analyis of the pleural effusion with two immunocytochemistry markers in favor of MPM and two excluding the diagnosis are sufficient to diagnose MPM. The aim of this review is to summarize recent diagnostic methods in MPM diagnosis.

Keywords

cytology; imaging; immunohistochemistry; malignant mesothelioma

Hrčak ID:

261186

URI

https://hrcak.srce.hr/261186

Publication date:

1.9.2021.

Article data in other languages: croatian

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