Case report
COVID-19 REINFECTION IN A PATIENT WITH ENDSTAGE RENAL DISEASE ON CHRONIC HEMODIALYSIS: IS IT POSSIBLE OR IS IT INACCURACY OF TESTING?
ALMA MUTEVELIĆ-TURKOVIĆ
orcid.org/0000-0002-3579-5689
; Sarajevo University Clinical Centre, Department of Hemodialysis, Sarajevo, Bosnia and Herzegovina
AMELA BEĆIRAGIĆ
; Sarajevo University Clinical Centre, Department of Hemodialysis, Sarajevo, Bosnia and Herzegovina
AMELA DERVIŠEVIĆ
; University of Sarajevo, School of Medicine, Department of Human Physiology, Sarajevo, Bosnia and Herzegovina
AIDA ĆORIĆ
; Sarajevo University Clinical Centre, Department of Hemodialysis, Sarajevo, Bosnia and Herzegovina
Abstract
Patients with end-stage renal disease (ESRD) on hemodialysis (HD) are at a high risk of acquiring SARS-CoV-2 and of developing severe COVID-19 and death. The possibility of being reinfected with this virus is poorly understood. To date, there are a small number of reports of reinfections in COVID-19 patients, especially in HD patients, with only four cases described so far. The aim was to show the possibility of reinfection and developing severe acute respiratory syndrome in HD patients. We describe a 69-year-old ESRD patient who had been on HD treatment for three years, with diabetes mellitus and a history of ischemic cardiomyopathy. The patient was tested for SARS-CoV-2 by a nasopharyngeal polymerase chain reaction (PCR) test because of a positive cluster at his dialysis unit and initially diagnosed with COVID-19 in July 2020. In this period, he had mild symptoms for a few days and remained asymptomatic afterwards. Four months later, he presented to the hospital with fatigue, high fever and shortness of breath, and was COVID-19 positive again. This case points to the possibility of reinfection, lack of immune response after an asymptomatic or mild infection, or even the possibility of the fi rst false-positive PCR test. Future longitudinal studies are needed to evaluate the potential reinfections, recurrence, and duration of antibody detection.
Keywords
chronic kidney disease; hemodialysis; COVID-19 reinfection
Hrčak ID:
261273
URI
Publication date:
10.8.2021.
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