Conference paper

CLOZAPINE: PROMISING TREATMENT FOR SUICIDALITY IN BIPOLAR DISORDER

Alina Wilkowska ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland
Mariusz S. Wiglusz ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland
Wiesław J. Cubała ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland

Abstract

Bipolar disorder is associated with the highest risk of completed suicide of all mental disorders. The suicide mortality of people
with bipolar disorder is approximately 25 times higher than the general population. No approved pharmacological strategies for
suicidality in bipolar disorder have been introduced so far. There is evidence for anti-suicidal effect of clozapine in schizophrenia.
Clozapine with its unique pharmacology, anti-aggressive and anti-impulsive properties is potentially an effective strategy for
suicidality in bipolar disorder.

Keywords

clozapine - bipolar disorder - suicidality - treatment resistance

Hrčak ID:

264176

URI

https://hrcak.srce.hr/264176

Publication date:

4.9.2019.

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