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Original scientific paper

CORRELATION OF CLINICAL AND ENDOSCOPIC INDICES IN IBD PATIENTS IN UNIVERSITY CLINICAL HOSPITAL MOSTAR

Emil Babić ; Department of Gastroenterology and Hepatolog, University Hospital Center Mostar, Mostar, Bosnia and Herzegovina
Milenko Bevanda ; Department of Gastroenterology and Hepatolog, University Hospital Center Mostar, Mostar, Bosnia and Herzegovina
Maja Karin ; Department of Gastroenterology and Hepatolog, University Hospital Center Mostar, Mostar, Bosnia and Herzegovina
Mile Volarić ; Department of Gastroenterology and Hepatolog, University Hospital Center Mostar, Mostar, Bosnia and Herzegovina
Danijel Bevanda ; Department of Gastroenterology and Hepatolog, University Hospital Center Mostar, Mostar, Bosnia and Herzegovina
Daniela Bevanda Glibo ; Department of Gastroenterology and Hepatolog, University Hospital Center Mostar, Mostar, Bosnia and Herzegovina
Ante Bogut ; Department of Gastroenterology and Hepatolog, University Hospital Center Mostar, Mostar, Bosnia and Herzegovina


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Abstract

Background: To explore correlation between clinical and endoscopic indices in inflammatory bowel disease (IBD) patients.
Subjects and methods: There were 112 patients with inflammatory bowel disease. All patients with diagnosed IBD was established a degree of clinical and endoscopic disease activity. CDAI (Crohn's disease activity index) was used as clinical and SESCD (Simplified Endoscopic Crohn Disease Index) as endoscopic index for Crohn's disease. For ulcerative colitis Truelov & Witts index was used as clinical and Baron as endoscopic activity index. Correlation of clinical and endoscopic indices were compared in Crohn disease (CD) and ulcerative colitis (UC). Patients were analyzed by clinical entities - CD and UC, according to sex, age, parameters of anemia, duration of disease and education.
Results: In the total of 112 IBD patients there were 69 patients diagnosed as ulcerative colitis (61.6%) and 43 as Crohn's disease (38.4%). There were 58 (51.8%) women and 54 (48.2%) men. Comparison between endoscopic and clinical indices in CD and UC demonstrated no significant differences in ilnness activity. Endoscopic and clinical disease activity was associated with a higher inflammatory parameters (CRP and leucocytes, L) and lower parameters of hemoglobin (Hb) and MCV.
Conclusion: Our research has established a good correlation between clinical and endoscopic index of disease activity in the CB
and UC in inflammation. Clinical indices can be used for monitoring inflammation.

Keywords

inflammatory bowel disease; endoscopic and clinical indices; CDAI (Crohn's disease activity index); SES-CD (Simplified Endoscopic Crohn Disease Index); Truelov & Witts; Baron index

Hrčak ID:

264274

URI

https://hrcak.srce.hr/264274

Publication date:

18.10.2016.

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