Medicina Fluminensis, Vol. 57 No. 4, 2021.
Review article
https://doi.org/10.21860/medflum2021_264893
Prevention and treatment of mucositis in patients suffering from malignant hematological diseases: an overview of the subject matter and the attitude of the Croatian cooperative group for hematologic diseases KROHEM
Nika Popović
orcid.org/0000-0003-2783-2061
; Odjel za hematologiju, onkologiju i kliničku imunologiju, Opća bolnica Varaždin, Varaždin, Hrvatska
Marinka Mravak Stipetić
; Klinika za stomatologiju, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Antonela Lelas
; Zavod za hematologiju, Klinika za unutarnje bolesti, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Dražen Pulanić
; Zavod za hematologiju, Klinika za unutarnje bolesti, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Delfa Radić Krišto
; Zavod za hematologiju, Klinika za unutarnje bolesti, Klinička bolnica Merkur, Zagreb, Hrvatska
Igor Aurer
; Zavod za hematologiju, Klinika za unutarnje bolesti, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Toni Valković
; Zavod za hematologiju, Klinika za internu medicinu, Klinički bolnički centar Rijeka, Rijeka, Hrvatska; Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska
Abstract
Mucositis is the painful inflammation with lesions of the mucous membranes of the mouth and the gastrointestinal tract that commonly arises as an adverse effect of high dose chemotherapy and/or radiotherapy and during hematopoietic stem cell transplantation in patients suffering from malignant hematological diseases. Mucositis affects the patients’ quality of life and the outcome of treatment. This review article describes the risk factors, prevalence, clinical picture, prevention measures and treatment of mucositis in patients suffering from malignant hematological diseases, and contains an overview of the subject matter and the attitude of the Croatian Cooperative Group for Hematological Diseases KROHEM, in accordance with the current literature and valid global guidelines.
Keywords
hematologic diseases; mucositis; prevalence; quality of life; risk factors; treatment outcome
Hrčak ID:
264893
URI
Publication date:
1.12.2021.
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