Review article

https://doi.org/10.21860/medflum2021_264894

The role of vitamin D in neurologic diseases

Valentino Rački ; Klinika za neurologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska; Katedra za neurologiju, Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska
Eliša Papić ; Klinika za neurologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska
Vladimira Vuletić ; Klinika za neurologiju, Klinički bolnički centar Rijeka, Rijeka, Hrvatska; Katedra za neurologiju, Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska

Abstract

Vitamin D is an essential nutrient necessary for the homeostasis of calcium and health of the skeletal system, with an increasing role in neurological diseases. All factors of vitamin D metabolism are present in the central nervous system, with autocrine and paracrine mechanisms of action. Vitamin D affects the levels of neurotrophic factors, regulates immune function and nervous system homeostasis. Vitamin D levels and supplementation is the subject of researches in most neurodegenerative diseases, with the lack associated with an increased disease risk. Researches in the field are promising, but there is a lack of high-quality studies needed for guidelines.

Keywords

central nervous system; neurodegenerative diseases; stroke; vitamin D

Hrčak ID:

264894

URI

https://hrcak.srce.hr/264894

Publication date:

1.12.2021.

Article data in other languages: croatian

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