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Medicina Fluminensis : Medicina Fluminensis, Vol. 57 No. 4, 2021.

Review article

https://doi.org/10.21860/medflum2021_264895

Metastasis of clear cell renal cell carcinoma to the larynx: a short literature review and presentation of a rare case of prolonged survival

Ilinko Vrebac ; Clinic of Otorhinolaryngology, Head and Neck Surgery, Clinical Hospital Center Rijeka, Rijeka, Croatia
Tamara Braut ; Clinic of Otorhinolaryngology, Head and Neck Surgery, Clinical Hospital Center Rijeka, Rijeka, Croatia; University of Rijeka, Faculty of Medicine, Rijeka, Croatia
Blažen Marijić ; Clinic of Otorhinolaryngology, Head and Neck Surgery, Clinical Hospital Center Rijeka, Rijeka, Croatia; University of Rijeka, Faculty of Medicine, Rijeka, Croatia
Dag Zahirović ; Clinic of Radiotherapy and Oncology, Clinical Hospital Center Rijeka, Rijeka, Croatia
Andrea Dekanić ; Clinical department of Pathology and Cytology, Clinical Hospital Center Rijeka, Rijeka, Croatia; University of Rijeka, Faculty of Medicine, Rijeka, Croatia
Jelena Vukelić ; Clinic of Otorhinolaryngology, Head and Neck Surgery, Clinical Hospital Center Rijeka, Rijeka, Croatia; University of Rijeka, Faculty of Medicine, Rijeka, Croatia
Matej Maršić ; Clinic of Otorhinolaryngology, Head and Neck Surgery, Clinical Hospital Center Rijeka, Rijeka, Croatia
Marko Velepič ; Clinic of Otorhinolaryngology, Head and Neck Surgery, Clinical Hospital Center Rijeka, Rijeka, Croatia; University of Rijeka, Faculty of Medicine, Rijeka, Croatia

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Abstract

Renal clear cell metastatic carcinoma of the larynx is an extremely rare diagnosis with poor survival. The objective of this short review is to provide insight into current state of literature on this rare neoplasm. Additionally we include the case of a patient with metastatic process of the thyroid cartilage that was treated with novel targeted therapies which enabled prolonged survival and good quality of life. These findings support their inclusion in treatment protocols of patients with metastatic renal clear cell carcinoma of the larynx, especially in those refusing surgery which is the main treatment option in literature so far.

Keywords

clear cell renal cell carcinoma; intensity-modulated radiotherapy; larynx; neoplasm metastasis; quality of life; targeted therapy

Hrčak ID:

264895

URI

https://hrcak.srce.hr/264895

Publication date:

1.12.2021.

Article data in other languages: croatian

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