Conference paper
NEUROCOGNITIVE MANAGEMENT OF THE PRIMARY NEGATIVE SYMPTOMS OF SCHIZOPHRENIA: A ROLE OF ATYPICAL ANTIPSYCHOTICS
Francesco Franza
orcid.org/0000-0002-2263-3699
; Consultant Mental Health Department “Villa dei Pini”, Avellino, Italy
Gabriella Carpentieri
; Psychologist, Neamente Association, Avellino, Italy
Serena De Guglielmo
; Psychologist, Neamente Association, Avellino, Italy
Vincenzo Fasano
; Psychologist, Neamente Association, Avellino, Italy
Nicoletta Fiorentino
; Consultant Mental Health Department “Villa dei Pini”, Avellino, Italy
Mariangela Perito
; Psychologist, Neamente Association, Avellino, Italy
Barbara Solomita
; Psychologist, Neamente Association, Avellino, Italy
Gianfranco Del Buono
; Psychiatric Department “University Salerno”, Salerno, Italy
Abstract
Patients with schizophrenia have profound and disabling cognitive deficits while negative symptoms represent a separate
symptom domain, with respect to depression, neurocognition, and social cognition. Particularly, primary negative symptoms of
schizophrenia represent a diagnostic and therapeutic challenge, In this study we try to evaluate the cognitive symptoms in 51
primary negative schizophrenic inpatients by the administration of simple, fast and understandable scales (MMSE, DSST, EpiTrack,
PANSS cognitive factor). We also evaluate the correlation with some SGAs (aripiprazole, quetiapine, olanzapine, paliperidone). Our
results support the evidence of the use of simple, rapid and acceptable scales for cognitive evaluation in clinical practice. Overall
data indicate no statistically significant variations of the negative symptomatology in all the examined sample, although a reduction
of the statistical averages in each group is observed (paliperidone and olanzapine, particularly).
Keywords
negative symptoms schizophrenia; atypical antipsychotics; cognitive deficits; effectiveness
Hrčak ID:
264919
URI
Publication date:
30.8.2016.
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