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Psychiatria Danubina, Vol. 26 No. suppl 1, 2014.

Conference paper

DO ATYPICAL ANTIPSYCHOTICS IMPROVE COGNITION?

Yasmin Walters ; University of Cambridge, School of Clinical Medicine, St. Catharine’s College, Cambridge, UK
Mark Agius ; Clare College Cambridge, The University of Cambridge, Cambridge, UK ; South Essex Partnership University Foundation Trust, UK ; Department of Psychiatry, University of Cambridge, Cambridge, UK

Full text: english pdf 287 Kb

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Abstract

One of the major symptoms of schizophrenia is cognitive deficits. Despite this, these impairments still lack an effective treatment.
It was hoped that atypical antipsychotics would treat these symptoms better than their first generation counterparts, but
unfortunately the likes of quetiapine and clozapine did not do so. Asenapine and lurasidone, two newer atypicals, have shown
promise, as have agents that interact with the glutamate system. Another approach has been to add agents such as modafinil. More
research is needed to consolidate the findings of these studies.

Keywords

schizophrenia; atypical; antipsychotic; cognition; asenapine; lurasidone; CATIE; glutamate; modafinil

Hrčak ID:

265732

URI

https://hrcak.srce.hr/265732

Publication date:

5.11.2014.

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