Original scientific paper
Serum Cholesterol Concentrations in Suicidal and Non-Suicidal Male Patients Suffering from Persistent Delusional Disorder
Darko Marčinko
Anita Marčinko
Mladen Lončar
Miro Jakovljević
Veljko Đorđević
Rudolf Gregurek
Neven Henigsberg
Petra Folnegović Grošić
Vera Folnegović Šmalc
Abstract
Suicidal behavior is a major health risk in psychiatric disorders, especially in affective and psychotic disorders. The
neurobiology of suicidal behavior is still unclear. Suicidality has been related to a reduced cholesterol levels. The aim of
this study was to evaluate serum cholesterol concentrations in suicidal and non-suicidal men suffering from persistent
delusional disorder and in healthy volunteers. Results showed that serum cholesterol concentrations were significantly
lower in suicidal than in non-suicidal patients and healthy controls. Also, level of psychopathology (measured by Brief
Psychiatric Rating Scale) is significantly marked in the group of suicidal patients, which indicates the importance of detecting
some clinical symptoms in patients with persistent delusional disorder in order to prevent suicidal behavior.
Keywords
suicidality; persistent delusional disorder; cholesterol; men
Hrčak ID:
24563
URI
Publication date:
13.5.2008.
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