Original scientific paper

Temporal Lobe Volume in Disorders with Psychotic Features

Elizabeta Radonić
Neven Henigsberg
Marko Radoš
Ninoslav Mimica
Vera Folnegović-Šmalc

Abstract

Since early neuropathological findings, temporal lobe has been related to the pathophysiology of some disorders with
psychotic features. The aim of this study was to compare temporal lobe volumes and asymmetry differences in patients
with schizophrenia, schizoaffective and bipolar disorders, disorders that cover the whole psychotic spectrum.
Temporal lobe volumes were estimated using high resolution magnetic resonance imaging in 60 subjects, 15 subjects
in each patient and one healthy volunteer (control) group. There are no statistically significant differences in temporal
lobe volumes among patient and control groups. Comparison of left and right temporal lobes shows that left temporal
lobes are smaller than right temporal lobes, however this difference reaches statistical significance only in groups of patients
with schizoaffective and bipolar disorders. Overall temporal lobe volume may be less informative in respect to
neuropathology of disorders with psychotic features than volumes of specific temporal lobe structures, in particular medial
temporal lobe structures.

Keywords

temporal lobe volume; schizophrenia; schizoaffective disorder; bipolar disorder

Hrčak ID:

24568

URI

https://hrcak.srce.hr/24568

Publication date:

13.5.2008.

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