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Collegium antropologicum, Vol. 32 - Supplement 1 No. 1, 2008.

Original scientific paper

Neurodevelopmental Outcome in Children with Periventricular Leukomalacia

Biserka Rešić
Maja Tomasović
Radenka Kuzmanić-Šamija
Marin Lozić
Jasminka Rešić
Mirsala Solak

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page 143-147

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Abstract

The purpose of this study was to question the correlation of different grades of periventricular leukomalacia (PVL)
and subsequent neurodevelopmental outcome. In a prospective study we followed 52 preterm infants. Infants were divided
into three groups according to their cranial ultrasound findings of PVL (De Vries classification). Seventeen children
had PVL 1, 20 children had PVL 2, and 15 children had PVL 3. All 15 (100%) children with PVL 3 developed cerebral
palsy with additional visual perceptual dysfunctions and epilepsy. Children with PVL 1 had high frequency of mild
neuromotoric delay and visual impairment. PVL 2 and 3 have great predictive value for subsequent severe neurodevelopmental
disorder which refers to cerebral palsy, different cognitive deficits, vision impairment and epilepsy. We have
determined that due to high frequency of visual impairment and epilepsy we need to include neurophysiologic examinations
very early in children with PVL lesions.

Keywords

periventricular leukomalacia; neurodevelopment; epilepsy; cerebral palsy; visual impairment

Hrčak ID:

24569

URI

https://hrcak.srce.hr/24569

Publication date:

13.5.2008.

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