Review article

Mesenchymal stem cells in orthopedics - a current perspective

Dragan Primorac ; St. Catherine Specialty Hospital, Zabok/ Zagreb, Croatia
Vid Matišić ; St. Catherine Specialty Hospital, Zabok/ Zagreb, Croatia
Vilim Molnar ; St. Catherine Specialty Hospital, Zabok/ Zagreb, Croatia
Vitorio Perić ; University hospital Merkur, Department of radiology, Zagreb, Croatia
Marina Dasović ; University of Zagreb, School of Medicine, Zagreb, Croatia

Abstract

Osteoarthritis is a common condition that can affect any joint in the body. It is encountered in all age groups, but
with a higher incidence in the older population. There is no treatment currently available that would prevent the
development or progression of osteoarthritis and the gold standard end-stage treatment is still total joint replacement
surgery, which is not without its risks. Therefore, new approaches are considered daily to treat patients that are
not yet at end-stage osteoarthritis, but still experience the most common symptoms of pain and joint dysfunction.
Mesenchymal stem cell research offers new opportunities for osteoarthritis treatment as their paracrine effect exhibits
clinical improvement in osteoarthritis patients, providing much-needed minimally invasive treatment options.

Keywords

osteoarthritis, regenerative medicine, MSCs, lipoaspiration

Hrčak ID:

270503

URI

https://hrcak.srce.hr/270503

Publication date:

28.3.2021.

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