Review article

COVID-19 severity determinants – modulating effect of environmental factors

Dragan Primorac ; St. Catherine Specialty Hospital, Zabok/ Zagreb, Croatia
Vid Matišić ; St. Catherine Specialty Hospital, Zabok/ Zagreb, Croatia
Vilim Molnar ; St. Catherine Specialty Hospital, Zabok/ Zagreb, Croatia
Marina Dasović ; University of Zagreb, School of Medicine, Zagreb, Croatia
Gordan Lauc ; University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia

Abstract

The new coronavirus that appeared in 2019 (SARS-CoV-2) caused the COVID-19 pandemic, which is responsible
for over a million confirmed deaths in 2020, making it the most important event of the 21st century thus far and
making SARS-CoV-2 the most scientifically studied virus. Most of those infected with the SARS-COV-2 virus (about
80%) recover quickly from the disease, showing minimal signs of inflammation, mostly similar to the common cold.
We analyzed the possible explanations of this observation and demonstrated the association of relative humidity,
temperature and IgG N-glycosylation with COVID-19 severity.

Keywords

SARS-CoV-2, pandemic, humidity, temperature, glycans

Hrčak ID:

270506

URI

https://hrcak.srce.hr/270506

Publication date:

28.3.2021.

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