Professional paper
https://doi.org/10.37797/ig.41.2.3
Urogenital tract candidiasis
Tomislava Skuhala
orcid.org/0000-0003-0129-1519
; University Hospital for Infectious Diseases "Dr. Fran Mihaljevic", Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Silvija Šoprek
orcid.org/0000-0002-5413-8393
; University Hospital for Infectious Diseases "Dr. Fran Mihaljevic", Zagreb, Croatia
Marijan Marić
orcid.org/0000-0002-5002-3492
; Department of Urology, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Marin Rimac
orcid.org/0000-0003-1617-4921
; School of Medicine, University of Zagreb, Zagreb, Croatia
Ivana Japirko
; University Hospital for Infectious Diseases "Dr. Fran Mihaljevic", Zagreb, Croatia
Abstract
Candida spp. is part of the normal microbiota of the human gastrointestinal and urogenital tracts, however, in some circumstances, can cause infections - mucocutaneous or disseminated. The most common causative pathogen is Candida albicans.
Vulvovaginal candidiasis is the most common type of mucocutaneous candidiasis, and its occurrence is more frequent in conditions characterised by elevated levels of oestrogen, use of antibiotics, corticosteroids, as well as in patients with diabetes or HIV.
The infection can also affect the bladder, but also the kidneys, most often ascending from the lower part of the urinary system.
In the period between January 1, 2018 and December 31, 2019, a total of 51.144 urogenital tract samples were analysed at the Laboratory for Microbiology of the University Hospital for Infectious Diseases “Dr. Fran Mihaljević“, 17.949 of which (35,1%) were positive.
Among detected isolates, candida accounted for 1.001 isolates (5,6%). Since the occurrence of various types of candida in urogenital tract is frequent, the aim of this paper was to present the clinical manifestations of candidiasis, treatment indications as well as the choice of antifungal drugs.
Urogenital tract candidiasis presents an important part of everyday clinical practice in both hospitalized patients as well as in outpatients. Careful interpretation of urinalysis results, urine culture test and disease symptoms, if present, are the key factors for differentiating colonisation from infection.
Keywords
Candida spp.; urinary tract candidiasis; vulvovaginal candidiasis; treatment
Hrčak ID:
270532
URI
Publication date:
10.1.2022.
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