Original scientific paper
SERUM PROTEIN CHANGES IN RABBITS AFTER CHRONIC ADMINISTRATION OF LEAD AND CADMIUM
Hristo Hristev
; Agricultural University – Plovdiv, Bulgaria
Dimo Penkov
; Agricultural University – Plovdiv, Bulgaria
Abdul Karim Hallak
; Albaath University – Homos, Syria
Maria Kirova
; State veterinary control – Plovdiv, Bulgaria
Bayko Baykov
; New Bulgarian University – Sofi a, Bulgaria
Atanas Bliznakov
; New Bulgarian University – Sofi a, Bulgaria
Abstract
The infl uence of lead (5mg/kg b.w) and cadmium (2mg/kg b.w) after chronic treatment of the rabbits on serum protein is investigated. Signifi cantly raised content of the cholesterol, ASAT and ALAT; hypo-albuminemia and hyperbetaglobulinemia of the background of one hypoproteinemia and low A/G coeffi cient are established. On basis of obtained result can to show degree of liver parenchyma damage and as trial for used the hyperbeta-globulinemia (at chronic treatment with cadmium is stronger markedly) as indicator for delimitation of enteral from parenteral toxication, at that is noted hypergamma-globulinemia.
Keywords
serum proteins; lead; cadmium; cholesterol; transpherase
Hrčak ID:
24900
URI
Publication date:
30.5.2008.
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