Conference paper
METABOLIC SYNDROME, MORBIDITY AND MORTLITY IN THE ERA OF COVID-19 PANDEMIC
Ivan Pećin
; Department of Internal Diseases, University Hospital Center Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Željko Reiner
; Department of Internal Diseases, University Hospital Center Zagreb, Zagreb, Croatia ; School of Medicine, University of Zagreb, Zagreb, Croatia
Abstract
The prevalence of obesity, diabetes, arterial hypertension and cardiovascular and cerebrovascular diseases is increasing
worldwide. Nowdays we are witnessing a pandemic of metabolic syndrome and obesity and an epidemic of these diseases in Croatia
as well. Moreover, every second Croatian citizen dies because of cardiovascular diseases. Visceral obesity, diabetes, dyslipidemia
and arterial hypertension tend to cluster forming a syndrome that we call metabolic syndrome. The concept of metabolic syndrome
was defined several decades ago as visceral type of obesity, hypertriglyceridemia, low HDL-cholesterol, arterial hypertension and
diabetes mellitus (insulin resistance). Most widely used definition is the one by National Education Cholesterol Program, NCEP -
Adult treatment Panel III - ATP III . Therefore, visceral obesity is considered as one of the greatest risks for mortality worldwide.
COVID pandemia increased the risk od deaths especially among patients with metabolic syndrome. Pandemia perpetuated several
other socio-economical risk factors (stress, depression, physical inactivity, devian strongly influence
cardiovascular health. Unfortunately, SARS-COV-2 virus enters the host (human) cell using signaling pathways (ANG II Rc) known
very well from the metabolic syndrome research and connecting those two entities predesponing these patients for a much worse
prognosis when infected with SARS-COV-2 virus. To conclude - chronic obesity pandemia goes hand by hand with novel COVID-19
pandemia dramatiacally increasing the risk of severe morbidity and mortality.
Keywords
Hrčak ID:
271693
URI
Publication date:
19.10.2021.
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