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Acta Dermatovenerologica Croatica, Vol. 29 No. 4, 2021.

Original scientific paper

Infantile Hemangiomas with Minimal or Arrested Growth – Do They Occur More Often in Premature Infants Than It Seemed?

Aleksandra Matić orcid id orcid.org/0000-0002-5118-1580 ; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia
Milan Matić orcid id orcid.org/0000-0003-1979-8756 ; Dermatovenereological Clinic, Clinical Center of Vojvodina, Novi Sad, Serbia
Sonja Prćić orcid id orcid.org/0000-0002-4086-9996 ; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; 2Pediatrics Clinic, Institute for Child and Youth Health Care of Vojvodina, Novi Sad, Serbia
Milica Gajić orcid id orcid.org/0000-0002-2069-4586 ; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia

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Abstract

Infantile hemangiomas with minimal or arrested growth (IH-MAGs)
are a subtype of infantile hemangiomas (IHs), characterized by absent or minimal
(equal or less than 25% of the total IH surface area) proliferation. They are
less conspicuous than classical IHs, but can also be complicated by ulceration or
can be misdiagnosed as capillary malformations. The literature on IH-MAGs is
scarce, but with increasing interest in the literature. We investigated the clinical
and epidemiological characteristics of IH-MAGs in a retrospective series of cases
found in a regional tertiary-care pediatric clinic during a 7-year period. Eleven
infants with 14 IH-MAGs were included in the analysis. There were 7 girls and
4 boys. Unlike the majority of other authors, we have found 7 premature and 4
full-term infants in our case series. Most of the IH-MAGs were classified as focal
(78.57%), were present at birth (72.72%), and were located on the lower body,
below the waist line (71.42%). In almost all infants, erythematous background as
well as vasoconstricted patches and/or halos were present, while fine or coarse
telangiectasias were observed mainly in full-term infants. A subtle proliferative
component was observed in only one case on follow-ups. There were no ulcerations.
The therapy – topical and oral beta-blocker – was introduced in two cases
of IH-MAGs in the face region. Clinical characteristics of IH-MAGs in our case series
were similar to those found in other studies on this subject. However, we
found a significantly higher percentage of premature infants with IH-MAGs than
in any available reference

Keywords

hemangioma, infant, premature, telangiectasia

Hrčak ID:

274682

URI

https://hrcak.srce.hr/274682

Publication date:

15.12.2021.

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