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Professional paper

https://doi.org/10.21860/medflum2022_275136

Urinary tract infections in kidney transplant recipients occurring in the first post-transplantation year

Petra Smajić orcid id orcid.org/0000-0002-7015-713X ; Sveučilište Josipa Jurja Strossmayera u Osijeku, Medicinski fakultet, Osijek, Hrvatska
Matea Smajić orcid id orcid.org/0000-0001-7448-3349 ; Sveučilište Josipa Jurja Strossmayera u Osijeku, Medicinski fakultet, Osijek, Hrvatska
Lada Zibar ; Klinička bolnica Merkur, Zagreb, Hrvatska


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Abstract

Aim: To investigate the frequency of urinary tract infections (UTI) in kidney transplant (KT) recipients occurring in the first post-transplant year, and the relationship between the frequency of UTI, immunosuppressive therapy (IT) and kidney graft function. Patients and methods: 114 patients were enrolled into the study (60.5 % men, median age 52 years; interquartile range 45 - 58). Data were taken from medical records and statistically processed by the IBM® SPSS® Statistics 25.0 software, at statistical significance level of P < 0.05. Results: Within one year following the KT, a total of 170 UTI episodes were reported in 67 out of 114 patients (58.8 %), caused by a total of 21 different agents. Asymptomatic bacteriuria (44.1 %) was noted as the most common clinical presentation, while the most frequently isolated cause of UTI in all clinical presentations was E. coli (38.9 %). In most cases, UTI occurred within the first 3 months after the KT (58.2 %), during the period in which the patients had a Foley catheter and/or JJ stent. UTI was significantly more common in women and in elderly persons. Patients on corticosteroids as part of their IT, had a significantly higher number of UTI episodes (P = 0.02) at the end of the first post-transplant year. Conclusion: More than a half of the participants had some form of UTI in the first post-transplantation year, with E. coli as the most frequently isolated cause. Higher UTI frequency was observed in women and the elderly who took more powerful IT (corticosteroids), and within the first 3 months following the KT.

Keywords

immunosuppression therapy; kidney; transplantation; urinary tract infections

Hrčak ID:

275136

URI

https://hrcak.srce.hr/275136

Publication date:

1.6.2022.

Article data in other languages: croatian

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