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Pitfalls in diagnosis of pilomatrixoma by fna and scraping cytology – report of seven cases
Vesna Ramljak
; Department of Cytology, University Hospital for Tumors, Zagreb, Croatia
Irena Ranogajec
; Department of Cytology, University Hospital for Tumors, Zagreb, Croatia
Irena Novosel
; Department of Pathology, ''Dr Ivo Pedišić'' General Hospital, Sisak, Croatia
Danijel Došen
; Department of Head and Neck Surgery, University Hospital for Tumors, Zagreb, Croatia
Danko Velimir Vrdoljak
; Department of Surgical Oncology, University Hospital for Tumors, Zagreb, Croatia
Abstract
Background: Pilomatrixoma is a benign tumor with differentiation toward hair cells. It is a rare, benign, slow-growing skin tumor firstly described by Malhebre and Chenantais in 1880. It usually occurs as a solitary lesion mostly located in the head and neck as a firm, deep-seated nodule covered by normal skin.
Case: Our study evaluate retrospectively the clinical and cytomorphologic features of seven cases of pilomatrixoma.
In the smears stained with MGG malignancy was excluded. The diagnosis of pilomatrixoma was confirmed by pathologist. A semiquantitative method was used in evaluation of the following features: basaloid cells, shadow cells, inflammatory cells, giant cells, naked nuclei, and debris (0 absent, 1+ mild amount, 2+ moderate, 3+ abundant).
The maximum score obtained in FNA was for basaloid cells 13/21, shadow cells 14/21 and giant cells 11/21 while in the histological sections, the maximum score for basaloid cells was 20/21 and for shadow cells 17/21.
Conclusion: The presence of basaloid cells, ghost cells and giant cells in cytological smears and also clinical information as a localization in the head and neck region, then a slowly growing tumor of the skin or subcutaneous tissue will allow a conclusive diagnosis of pilomatrixoma by FNA.
Keywords
pilomatrixoma; FNA cytology; skin adnexa
Hrčak ID:
281772
URI
Publication date:
20.12.2004.
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