Original scientific paper
https://doi.org/10.26800/LV-144-supl3-2
Early and final outcome of patients suffered from muscle weakness aquired in COVID Intensive Care Unit – How precise we can be about eary and final outcome of patients at the time of the end of mechanical ventilation?
Jelena Gulišija
; Klinika za neurologiju, Klinički bolnički centar Split
Vesna Čapkun
; Klinički zavod za nuklearnu medicinu, Klinički bolnički centar Split
Sanda Stojanović Stipić
; Klinika za anesteziologiju, reanimatologiju i intenzivno liječenje, Klinički bolnički centar Split
Supplements: 00d_SADRZAJ.pdf
Abstract
Critical illness refers to all medical life-threatening condition that should be treated in Intesive care unit (ICU). According to literature, about 50–80 % patients treated in ICU because of critical illness develop Intensive care unit – aquired weakness, ICUAW. It is defined as diffused, generalised muscle weakness that could only be explained by critical illness. Unsuccessful weaning from ventilator is very often associated with this condition and it causes more complications, prolonges hospitalization and increases health-care related costs. Considering all of this, ICUAW is very important to notice, prevent and treat. Aim of the study: Define the ICUAW incidence of ICU patients and compare the early and final outcome of patients who had sufficient muscle strenght to those who developed ICUAW. Eary outcome refers to need to reintubation of patient and final outcome refers to survival
or death outcome. Material and methods: The research was done in COVID ICU Clinic of anesthesia, reanimatology and intensive care during the February 2022. All pateint that were mechanicaly ventilated more than 48 h, and weaned from ventilator successfuly were included. All patient that had a muscle or neurologic disorder were excluded. The patients were examined after abolition of analgosedation and after weaning from ventilator. The diagnosis was made clinically by Medical Research Council test (MRC test). Results: During the February 2022 in COVID ICU, 77 patients were treated. In this group 36 patients were successfully weaned from ventilator in a period longer than 24 hours and 12 patients developed ICUAW, one patient becuase of impared consciousness was not able to be examined. We determined that group that develop ICUAW needed prolonged mechanical ventilantion, there was more need for reintubation and there was a higher probability of mortal outcome. Conclusion: ICUAW is very often complication of patient treated in ICU. Considering the fact that it prolonges mechanical ventilation, hospitalization and increases healtcare cost it is very important to prevent and treat this condition. Further investigation will be needed to define the exact etiopathogenesis in order to prevent ICUAW and treat propertly.
Keywords
INTENSIVE CARE UNIT – AQUIRED WEAKNESS; CRITICAL ILLNESS; MYOPATHY AND POLYNEUROPATHY OF CRITICAL ILLNESS; COVID PANDEMIC
Hrčak ID:
284132
URI
Publication date:
25.9.2022.
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