Original scientific paper
https://doi.org/10.5599/jese.1366
A sensitive and simple electrochemical technique for detecting ascorbic acid content in pharmaceutical and biological compounds
Farideh Mousazadeh
; School of Medicine, Bam University of Medical Sciences, Bam, Iran
Sayed Zia Mohammadi
; Department of Chemistry, Payame Nour University, Tehran, Iran
Abstract
In the current study, a glassy carbon electrode (GCE) modified with graphene-CoS2 nanocomposite was investigated for electrochemical sensing of ascorbic acid. The electrochemical performance of the modified electrode was examined using differential pulse voltammetry (DPV), linear sweep voltammetry (LSV) and chronoamperometry (CHA) techniques. The electrochemical behavior of ascorbic acid at the graphene-CoS2/GCE displayed a higher oxidation current and lower oxidation potential than bare GCE. Under the optimal experimental conditions, the sensor presented a good linear response between the current and the ascorbic acid concentration range of 0.15–245.0 μM, with a low detection limit of 0.05 μM. Finally, the graphene-CoS2 nanocomposite-modified GCE was applied for the determination of ascorbic acid in real samples and displayed excellent recoveries.
Keywords
Glassy carbon electrode; graphene - CoS2 nanocomposite; sensors
Hrčak ID:
286874
URI
Publication date:
7.12.2022.
Visits: 211 *